Optimization of artificial lung ventilation

Department of Biomedical Technology, nám. Sítná 3105, Kladno, 272 01

prof. Ing. Karel Roubík, Ph.D., roubik@fbmi.cvut.cz, phone: +420 334 358498

Non-conventional Ventilatory Team (NVT)




Artificial lung ventilation is a highly effective method used in solving respiratory insufficiency or in the case of the failure of the patient’s spontaneous breathing. At the same time, however, artificial lung ventilation negatively affects and damages the patient’s respiratory system. The research objective is searching such artificial lung ventilation modes which minimize the undesirable effects on the patient’s lungs. particular, high-frequency ventilation applying very small breath volumes and small pressure amplitudes, which reduces the unfavourable effect of artificial lung ventilation. Research is aimed at technical problems related to high-frequency ventilation, the study of gas flows during high-frequency ventilation, the monitoring of high-frequency ventilation and, in cooperation with clinical workplaces, also at seeking a target patient group that may profit from high-frequency ventilation. Significant achievements include the development of a device called the “Demand Flow System” allowing spontaneous ventilation of patients connected to a high-frequency ventilator, which favourably affects patient’s respiratory system. The research team also deals with other non-conventional ventilation technologies, such as the use of heliox – a mixture of helium and oxygen where thanks to its physical characteristics heliox flows through the respiratory system with a much greater ease than air. Patients with obstructive lung diseases may breathe heliox spontaneously even in cases where they would not be able of spontaneous ventilation while breathing air and they would have to be connected to the ventilator.